Endotoxin Testing (Kinetic LAL Assay)

Endotoxin sample collection methods. Self Collection at Home 

Endotoxins are derived from the cell walls of Gram-Negative bacteria (GNB). Gram-negative bacteria are found almost anywhere in nature. Their toxins are found within the outer layer membrane of the GNB cell wall. They do not have to be living; both viable and non-viable gram-negative bacteria contribute endotoxins.

The most common routes of endotoxin exposure are inhalation and intestinal tract absorption via food or water. The health effects of endotoxins vary depending on the individual, dosage, and route of exposure. Elevated airborne concentrations are prevalent in sewage treatment plants, swine operations, cotton textile mills, poultry houses, and in water-damaged and flood-contaminated buildings.